For intravenous administration, what is the bioavailability F?

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Multiple Choice

For intravenous administration, what is the bioavailability F?

Explanation:
Bioavailability F is the fraction of an administered dose that reaches systemic circulation. For intravenous administration, the drug is delivered directly into the bloodstream, bypassing absorption barriers and first-pass metabolism, so the entire dose becomes available systemically. Therefore, F equals 1 (or 100%). The other values would imply no delivery, partial delivery, or more drug in circulation than was given, which isn’t possible with IV administration.

Bioavailability F is the fraction of an administered dose that reaches systemic circulation. For intravenous administration, the drug is delivered directly into the bloodstream, bypassing absorption barriers and first-pass metabolism, so the entire dose becomes available systemically. Therefore, F equals 1 (or 100%). The other values would imply no delivery, partial delivery, or more drug in circulation than was given, which isn’t possible with IV administration.

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